
Our Publications
Welcome to Jacox Lab's collection of research manuscripts. Browse our publications below to learn more about our research and findings. If you have any questions or suggestions, do not hesitate to reach out to us.
Impacts of Jaw Surgery on Speech in Class III Patients
Rezende Silva, E., Bode, C.S., Lowry, G. et al. Impacts of jaw surgery on speech in Class III patients. Nat Commun (2026). https://doi.org/10.1038/s41467-026-71495-9.
Parent Perceptions of Animal-Assisted Therapy for Pediatric Dental Patients with Special Health Care Needs: A Pilot Survey Study
Roa V, Castro M, Sangalli L, Jacox L, Sawicki CM. Parent Perceptions of Animal-Assisted Therapy for Pediatric Dental Patients with Special Health Care Needs: A Pilot Survey Study. Pediatr Dent. 2026 Jan 15;48(1):38-46. PMID: 41803656.
Evaluating Effects of Animal-Assisted Therapy on Pediatric Dental Care Patients: A Pilot Clinical Trial
Massouda J, Ghaltakhchyan N, Judd J, Bocklage C, Selden R, TumSuden O, Nanney E, Lee J, Ginnis J, Strauman T, Sawicki C, Hodges EA, Graves C, Divaris K, Jacox L. Evaluating effects of animal-assisted therapy on pediatric dental care patients: A pilot clinical trial. J Am Dent Assoc. 2025 Jun;156(6):447-457.e14. doi: 10.1016/j.adaj.2025.03.006. PMID: 40467121; PMCID: PMC12356166.
A Software-based Observational Coding Approach for Evaluating Paediatric Dental Pain, Anxiety, and Fear
Bocklage C, Selden R, Tumsuden O, et al. A software-based observational coding approach for evaluating paediatric dental pain, anxiety, and fear. Int J Paediatr Dent. 2024; 00: 1-18. doi:10.1111/ipd.13227
Influence of BMI Percentile on Craniofacial Morphology and Development in Adolescents, Part II: Elevated BMI is Associated with Larger Final Facial Dimensions
Hancock, S., Carmack, A., Kocher, M., Rezende Silva, E., Sulkowski, T., Nanney, E., Graves, C., Mitchell, K., & Jacox, L. A. Influence of BMI percentile on craniofacial morphology and development in adolescents,Part II: Elevated BMI is associated with larger final facial dimensions. European Journal of Orthodontics. https://doi.org/10.1093/ejo/cjad043
Validating Spectral Moment Analysis as a Quantitative Measure of Speech Distortions in Speakers With Class III Malocclusions
Jhingree S, Xie Y, Bocklage C, et al. Validating Spectral Moment Analysis as a Quantitative Measure of Speech Distortions in Speakers With Class III Malocclusions. Perspect ASHA Spec Interest Groups. 2022;7(3):728-740. doi:10.1044/2022_persp-21-00315
Pediatrics, Craniofacial and Orthognathic Surgery Track: Impacts of Dentofacial Disharmony and its Surgical Correction on Speech
Jacox, Laura Anne, et al. “Pediatrics, Craniofacial and Orthognathic Surgery Track: Impacts of Dentofacial Disharmony and Its Surgical Correction on Speech.” Journal of Oral and Maxillofacial Surgery, vol. 81, no. 10, Oct. 2023, pp. e9–10. DOI.org (Crossref), https://doi.org/10.1016/j.joms.2023.08.187.
Patient and Caregiver Perceptions of Animal Assisted Activity in Orthodontics
Cass K, Bocklage C, Sulkowski T, Graves C, Ghaltakhchyan N, Rapolla A, Jackson T, Divaris K, Wiesen C, Strauman T, Jacox L. Patient and Caregiver Perceptions of Animal Assisted Activity in Orthodontics. Animals (Basel). 2022 Jul 21;12(14):1862. doi: 10.3390/ani12141862. PMID: 35883412; PMCID: PMC9312150.
Impacts of Development, Dentofacial Disharmony, and Its Surgical Correction on Speech: A Narrative Review for Dental Professionals
Bode C, Ghaltakhchyan N, Silva ER, et al. Impacts of Development, Dentofacial Disharmony, and Its Surgical Correction on Speech: A Narrative Review for Dental Professionals. Appl Sci (Basel). 2023;13(9):5496. doi:10.3390/app13095496
Longitudinal Outcomes of Bone-Anchored Maxillary Protraction Treatment
Esposito C, Judd J, Rezende Silva E, Xie J, Blakey G, Jacox LA. Longitudinal outcomes of bone-anchored maxillary protraction treatment. Am J Orthod Dentofacial Orthop. 2026 Jul 27:S0889-5406(26)00293-3. doi: 10.1016/j.ajodo.2026.04.018. Epub ahead of print. PMID: 42506953.
A Lingual Ultrasound Study of Speech in Patients With Cleft Lip and Palate Following Orthognathic Surgery
Lowry G, Rezende Silva E, Matthews J, Shoji A, Turvey T, Blakey G, Zajac D, Mielke J, Jacox LA. A Lingual Ultrasound Study of Speech in Patients With Cleft Lip and Palate Following Orthognathic Surgery. Orthod Craniofac Res. 2025 Apr 11. doi: 10.1111/ocr.12926.
A Cetylpyridinium Chloride Oral Rinse Reduces Salivary Viral Load in Randomized Controlled Trials
Graves C, Ghaltakhchyan N, Ngo TQ, Liu C, Babikow E, Shoji A, Bocklage C, Sang Y, Phillips ST, Bowman N, Frazier-Bowers S, Freire M, Wallet S, Divaris K, Wu D, Jacox LA. A Cetylpyridinium Chloride Oral Rinse Reduces Salivary Viral Load in Randomized Controlled Trials. JDR Clin Trans Res. 2024 Dec 9:23800844241296840. doi: 10.1177/23800844241296840.
Multitaper Spectrum Analysis of Consonants Produced by Patients With Dentofacial Disharmonies
Tran A, Oakley M, Paye C, et al. Multitaper Spectrum Analysis of Consonants Produced by Patients With Dentofacial Disharmonies. Journal of Speech, Language, and Hearing Research. doi:doi:10.1044/2023_JSLHR-23-00280
Longitudinal Microbiome Changes in Supragingival Biofilm Transcriptomes Induced by Orthodontics
Babikow E, Ghaltakhchyan N, Livingston T, et al. Longitudinal Microbiome Changes in Supragingival Biofilm Transcriptomes Induced by Orthodontics [published online ahead of print, 2023 Oct 24]. JDR Clin Trans Res. 2023;23800844231199393. doi:10.1177/23800844231199393
Educational Debt and the Gender Gap: Understanding Factors Influencing Orthodontists' Career Decisions
Worthington CC, Mihas P, Bocklage C, et al. Educational debt and the gender gap: Understanding factors influencing orthodontists' career decisions. Am J Orthod Dentofacial Orthop. 2022;161(1):e20-e61. doi:10.1016/j.ajodo.2020.10.027
Formation of a "Pre-mouth Array" from the Extreme Anterior Domain Is Directed by Neural Crest and Wnt/PCP Signaling
Jacox L, Chen J, Rothman A, Lathrop-Marshall H, Sive H. Formation of a "Pre-mouth Array" from the Extreme Anterior Domain Is Directed by Neural Crest and Wnt/PCP Signaling. Cell Rep. 2016 Aug 2;16(5):1445-1455. doi: 10.1016/j.celrep.2016.06.073. Epub 2016 Jul 14. PMID: 27425611; PMCID: PMC4972695.
A Novel Kinin-Kallikrein Pathway Regulates Vertebrate Mouth Formation
Sindelka, R., Jacox, L., Dickinson, A. and Sive, H. (2012), A novel kinin-kallikrein pathway regulates vertebrate mouth formation. FASEB J, 26: 339.1-339.1. https://doi.org/10.1096/fasebj.26.1_supplement.339.1
​Weight-Related Considerations for Orthodontic Treatment: A Quantitative Survey Study
Hezarkhani, Elmira, et al. “Weight-Related Considerations for Orthodontic Treatment: A Quantitative Survey Study.” AJO-DO Clinical Companion, July 2026, p. S2666430526001160. DOI.org (Crossref), https://doi.org/10.1016/j.xaor.2026.07.004.
Effects of Animal-Assisted Therapy on Dental Anxiety, Behavior, and Perceptions in Young Pediatric Patients: a Blinded Randomized Controlled Trial
Kapov G, Linton K, Gatewood C, Liu C, Strauman T, Hodges E, Graves C, Sawicki C, Wu D, Divaris K, Jacox LA. Effects of animal-assisted therapy on dental anxiety, behavior, and perceptions in young pediatric patients: a blinded randomized controlled trial. Trials. 2025 Aug 7;26(1):279. doi: 10.1186/s13063-025-08970-z. PMID: 40775655; PMCID: PMC12330074.
Immune Dysregulation in the Oral Cavity during Early SARS-CoV-2 Infection
Graves C, Babikow E, Ghaltakhchyan N, et al. Immune Dysregulation in the Oral Cavity during Early SARS-CoV-2 Infection. Journal of Dental Research. 2024;0(0). doi:10.1177/00220345241271943
Identifying Factors Influencing Orthodontic Residency Program Selection
Nanney EM, Shumaker A, Gutierrez T, et al. Identifying factors influencing orthodontic residency program selection. J Dent Educ. 2023; 1-10. https://doi.org/10.1002/jdd.13431
Impacts of Anterior-Posterior Jaw Disproportions on Speech of Dentofacial Disharmony Patients
Oliver S, Keyser MMB, Jhingree S, Bocklage C, Lathrop H, Giduz N, Moss K, Blakey G, White R, Turvey T, Mielke J, Zajac D, Jacox LA. Impacts of anterior-posterior jaw disproportions on speech of dentofacial disharmony patients. Eur J Orthod. 2023 Feb 10;45(1):1-10. doi: 10.1093/ejo/cjac057. PMID: 36308520; PMCID: PMC9912703.
Second Molar Eruption Disturbances in Borderline Extraction Orthodontic Patients
Patrick T, Stickrath K, Christensen J, Jacox L, Mitchell K. Second molar eruption disturbances in borderline extraction orthodontic patients. AJODO. 2024. https://doi.org/10.1016/j.ajodo.2024.06.016
Non-Random Sister Chromatid Segregation in Human Tissue Stem Cells
Panchalingam K, Jacox L, Cappiello BD, Sherley JL. Non-Random Sister Chromatid Segregation in Human Tissue Stem Cells. Symmetry. 2020; 12(11):1868. https://doi.org/10.3390/sym12111868
Role of the Extreme Anterior Domain Organizer in Craniofacial Development
Jacox L, Sindelka R, Chen J, Rothman A, Dickinson A, Sive H. The extreme anterior domain is an essential craniofacial organizer acting through Kinin-Kallikrein signaling. Cell Rep. 2014 Jul 24;8(2):596-609. doi: 10.1016/j.celrep.2014.06.026. Epub 2014 Jul 17. PMID: 25043181; PMCID: PMC4135435.